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Станислав Лукшанов
Во -первых,в самом предложении должно быть did,а не do.
Во-вторых,можно задать такие вопросы:
1.Did they come to the university in time yesterday?
2.Did they come to the university in time yesterday or not ?
3.Who didn't come to the university in time yesterday?
4.When did they come to the university yesterday?
5.They did not come in time to the university yesterday ,did they?